Journal of Shanghai Jiao Tong University (Medical Science) >

2018 , Vol. 38 >Issue 6: 695

DOI: https://doi.org/10.3969/j.issn.1674-8115.2018.06.020

Review

Application of drug-coated balloons in treatment of coronary small vessel diseases

  • YANG Gan ,
  • PU Jun ,
  • HE Ben
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  • Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China

Online published: 2018-07-03

Supported by

National Natural Science Foundation of China, 81625002, 81400261; National Key Research and Development Program of China, 2016YFC1301203; Project of Shanghai Shen Kang Hospital Development Center, 16CR1012A, 16CR3034A; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University, YG2016MS45, YG2015ZD04

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Abstract

Drug-coated balloons (DCB) have emerged as a new application in percutaneous coronary intervention. It is developed to circumvent some of the limitations faceddrug-eluting stents (DES). DES has some limitations, as follows: it could not be implanted in some lesions; bleeding risks are associated with prolonged dual antiplatelet therapy; risks of late and very late stent thrombosis increase. Many clinical trials had confirmed the efficacy and safety of DCB, particularly, the application of DCB in coronary small vessel diseases. This review discussed the basic concept, development, evolution of DCB and some clinical studies associated with the application of DCB in coronary small vessel diseases.

Key words： drug-coated balloon; drug-eluting stent; paclitaxel; coronary small vessel; percutaneous transluminal coronary angioplasty

Cite this article

YANG Gan , PU Jun , HE Ben . Application of drug-coated balloons in treatment of coronary small vessel diseases[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2018 , 38(6) : 695 . DOI: 10.3969/j.issn.1674-8115.2018.06.020

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