China University Subject Ranking (CUSR) and Essential Science Indicators (ESI) are important reference indicators for China medical discipline level. The main problems affected the development of medical discipline are the medical education mode failed to fit uniqueness of medical education, the limitations of the design of medical talent training, the low efficiency of medical clinical research ability and so on. Taking the construction of “top level” as the goal oriented and improving the medical discipline level, we need to grasp the following key links: to establish the medical education mode with respect to the special pattern of medical education, to build the medical talents highland with innovation course and incentive system, and to promote the developmentefficiencyof medicaldisciplinebased onthestandard management system and so on.