The patient was a 51-year-old female. She was admitted to the hospital becaof “repetitive convulsions for 1 month”. No significant neurological positive signs were found in the examination. D-dimer was in the normal range in several times of detection. Brain CT and electroencephalograph showed no obvious abnormality. Sustained hypoxemia occurred on admission, and CT imaging of pulmonary artery perfusion was performed. In the CT images bilateral distal main pulmonary arteries and their main branches showed vessel filling defect, partial lumen stenosis and occlusion, and bilateral small branches of pulmonary arteries showed extensive similar filling defect. Finally the patient was diagnosed with pulmonary embolism, whose condition was safter anticoagulation therapy with warfarin.