Journal of Shanghai Jiao Tong University (Medical Science) >

2019 , Vol. 39 >Issue 7: 795

DOI: https://doi.org/10.3969/j.issn.1674-8115.2019.07.019

Review

Research progress of neuroimmune mechanisms of cognitive function in schizophrenia and effect of atypical antipsychotic drugs on it

  • WANG Dan-dan ,
  • ZHANG Chen
Expand
  • Department of Biochemistry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China

Online published: 2019-08-26

Supported by

National Nature Science Foundation of China, 81471358；Western Medicine Guide Project of Shanghai Municipal Commission of Science and Technology, 14411969000; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Support, 20152530; Foundation of Shanghai Municipal Commission of Health and Family Planning, 201540029

Fold

Abstract

Atypical antipsychotic drugs have overcome the serious prolactin elevation and extrapyramidal symptoms of typical antipsychotic drugs, and become the first-line treatment for psychiatry. Studies have found that atypical antipsychotic drugs can modulate the immune inflammatory state of patients and affect their cognitive function, and there is increasing evidence suggesting that neuroimmune disorders may impair cognitive function in schizophrenia. This article reviews the progress of neuroimmune mechanisms of cognitive function in schizophrenia and the effect of atypical antipsychotic drugs on it.

Key words： antipsychotics; cognitive function; schizophrenia; neuroimmune

Cite this article

WANG Dan-dan , ZHANG Chen . Research progress of neuroimmune mechanisms of cognitive function in schizophrenia and effect of atypical antipsychotic drugs on it[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2019 , 39(7) : 795 . DOI: 10.3969/j.issn.1674-8115.2019.07.019

Options
Outlines

/

〈 〉