As a common mental disorder, panic disorder (PD) repeats unpredictably and negatively, influencing social function and life quality of patients. With the increasingly fierce social environment, the incidence of PD has been increasing yearyear which accounts for an increasing proportion of the global burden of disease. In recent years, research on the relationship between childhood trauma and PD has been increasing, which included the impact of multiple aspects of physical or emotional abuse, physical or emotional neglect, sexual abuse, and family dysfunction on PD. And as a predictor of PD, separation anxiety in childhood is closely related to PD. This paper reviews the research progress of childhood physical abuse, emotional abuse, sexual aband separation parents of PD patients.