Journal of Shanghai Jiao Tong University (Medical Science) >

2020 , Vol. 40 >Issue 2: 255

DOI: https://doi.org/10.3969/j.issn.1674-8115.2020.02.018

Review

Effect of cytoskeleton-associated protein 4 on tumor diagnosis and prognosis

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  • 1. Radioimmunology and Clinical Laboratory, Luwan Branch, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China; 2. Department of Clinical Laboratory, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Online published: 2020-03-20

Supported by

National Natural Science Foundation of China (81871706); "Science and Technology Innovation Action Plan" Projects in Industry-University-Research-Medical Cooperation Fields of Shanghai (17DZ1930301-26); Shanghai Municipal Planning Commission of Science and Research Fund (201840227, 201740069); Shanghai Huangpu District Municipal Planning Commission of Science and Research Fund (HKM201702).

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Abstract

Cytoskeleton-associated protein 4 (CKAP4), also known as p63, is a non-glycosylated type Ⅱ membrane protein. Expression of CKAP4 in tissues, cells and serum can be used as a diagnostic marker for a variety of tumors, and has a certain correlation with the prognosis of these tumors. This article reviews the subtype and function of CKAP4, as well as its research and application as a diagnostic and prognostic indicator of tumor.

Key words： cytoskeleton-associated protein 4 (CKAP4); p63; tumor marker; diagnosis; prognosis

Cite this article

LIU Jin-yan, ZHAO Jun-tao, WANG Heng-ru, HUANG Jia-yi, WANG Yu-ting, XIANG Ming-jie . Effect of cytoskeleton-associated protein 4 on tumor diagnosis and prognosis[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2020 , 40(2) : 255 . DOI: 10.3969/j.issn.1674-8115.2020.02.018

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