Review

Clinical progress of noninvasive follicular thyroid neoplasm with papillary-like nuclear features

  • 曾 素,许培培,郭明高
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  • Department of Surgery, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233

Online published: 2020-09-23

Supported by

National Natural Science Foundation of China (81672373).

Abstract

In 2015, the United States and Canadian Academy of Pathology re-evaluated noninvasive encapsulated follicular variant of papillary thyroid carcinomas (NI-EFVPC), and then the new terminology of "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) was initially introduced to replace NI-EFVPTC. In 2017, the World Health Organization also used NIFTP in the endocrine tumor classification. NIFTP is an encapsulated or clearly delimited noninvasive neoplasm with a follicular growth pattern and nuclear features of papillary thyroid carcinoma. Ultrasonography, cytology examination and genetic test are helpful to identify NIFTP, but the results overlap with invasive encapsulated follicular variant of papillary thyroid carcinoma. This paper mainly reviews the latest research in the clinical features, diagnosis and treatment features and prognosis of NIFTP.

Cite this article

曾 素,许培培,郭明高 . Clinical progress of noninvasive follicular thyroid neoplasm with papillary-like nuclear features[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2020 , 40(7) : 968 -973 . DOI: 10.3969/j.issn.1674-8115.2020.07.017

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