Objective · To evaluate the early outcomes of 3D printing-assisted fenestrated/branched endovascular repair (f/bEVAR) in the treatment of aortic diseases involving visceral branches. Methods · The clinical data of the patients with aortic diseases involving visceral branches treated by 3D printing-assisted f/bEVAR in the Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from May 2019 to May 2020 were retrospectively analyzed, including the surgical effect and the occurrence of perioperative complications. And the results of early follow-up were also evaluated. Results · A total of 13 patients were enrolled, including 11 males (84.6%), with an average age of (58.3±14.1) years. There were 7 cases of abdominal aortic aneurysm, 5 cases of dissecting aneurysm and 1 case of descending aorta aneurysm. The success rate of visceral branch artery reconstruction technique was 94.7%. One patient's right renal artery was covered by the main stent and was reconstructed by parallel stent technique. No postoperative complications, such as renal artery ischemia and intestinal ischemia, occurred, and the perioperative mortality rate was 0. The average follow-up time was (7.3±4.6) months. No patient died during the follow-up. No symptoms related to target organ damage occurred. The computed tomography angiography during follow-up showed that the blood flow of all branches was smooth. Conclusion · 3D printing-assisted f/bEVAR is a safe and effective method for the treatment of aortic diseases involving visceral branches.