Journal of Shanghai Jiao Tong University (Medical Science) >

2021 , Vol. 41 >Issue 2: 228 - 232

DOI: https://doi.org/10.3969/j.issn.1674-8115.2021.02.016

Review

Progress and prospect of in situ bioprinting

  • Wen-tao LI ,
  • Jin-wu WANG
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  • Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China

Received date: 2020-02-26

  Online published: 2021-02-28

Supported by

National Key Research and Development Program of China(2018YFB1105600);National Natural Science Foundation of China(81572156);Project of Science and Technology Commission of Shanghai Municipality(19XD1434200);Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support(20152224)

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Abstract

Bioprinting is a new biological manufacturing technology, which opens up new ways for regenerative therapy. The purpose of bioprinting is to create the internal plants in vitro. However, it is difficult to culture and vascularize printed tissue in vitro. In order to overcome this difficulty, in situ printing is presented to print the tissue directly on the injured or defective site, using the natural microenvironment in vivo to make the printed tissue mature. This article reviews the technology, advantages and research status of in situ bioprinting and briefly introduces the future direction of in situ bioprinting.

Key words： in situ bioprinting; tissue regeneration; bioink

Cite this article

Wen-tao LI , Jin-wu WANG . Progress and prospect of in situ bioprinting[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2021 , 41(2) : 228 -232 . DOI: 10.3969/j.issn.1674-8115.2021.02.016

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