·To investigate the interdependence between chronic kidney disease children's transition readiness assessment of children and their parents and the quality of life of both parties by using an Actor-Partner Interdependence Model.

·A convenience sample of 177 pairs of children with CKD aged 12?18 years who were hospitalized in the Nephrology Department of Shanghai Children′s Medical Center, Shanghai Jiao Tong University School of Medicine and Children′s Hospital of Shanghai, Shanghai Jiao Tong University from October 2018 to April 2021, and their parents were selected for the general information questionnaire and self-care and transition readiness and quality of life questionnaire, and a model was constructed by using AMOS 24.0 to analyze the correlations.

·The assessment of transition readiness of 177 children with CKD and their parents was unsatisfactory, with item average score of 3.39±0.62 for the children and 3.31±0.63 for the parents; the item average score of quality of life for the children and parents were 75.35±15.28 and 70.27±18.56, respectively. Multiple stratified regression analysis showed that the number of school days missed within six months was a negative predictor of the child′s quality of life; duration of illness, only child or not in a family, and mother unemployment were negative predictors of the parent′s quality of life, while doctor-patient communication between the child and the parent was a positive predictor for both parties. The results of the actor-partner interdependence model showed interdependence between child and parent assessment of the child′s transition readiness and quality of life of both parties, with an actor effect between parent transition readiness and parent quality of life (B=27.76, P=0.000) and a partner effect for both child and parent (child: B=-14.91, P=0.007; parent: B=14.35, P=0.000), and in the subdimensional analysis, there were actor-partner effects of varying degrees.

·There is a reciprocal relationship between child′s transition readiness by the child with CKD and his or her parents and the quality of life of both parties, and health care providers need to focus on parent-child interaction during the child-parent transition and include both the child and parents in the development of a targeted transition readiness plan to improve the quality of life of both parties.