Journal of Shanghai Jiao Tong University (Medical Science) >

2023 , Vol. 43 >Issue 7: 939 - 944

DOI: https://doi.org/10.3969/j.issn.1674-8115.2023.07.017

Review

Research progress of brain magnetic resonance imaging related to suicide in bipolar disorder patients

  • Jiaye CHEN ,
  • Huifeng ZHANG ,
  • Wenxian LU ,
  • Daihui PENG
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  • Department of Mood Disorder, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
PENG Daihui, E-mail: pdhsh@126.com.

Received date: 2022-12-14

  Accepted date: 2023-05-18

  Online published: 2023-07-28

Supported by

Central Funds Guiding Local Science and Technology Development of Shanghai(YDZX20213100001003);Foundation of Science and Technology Commission of Shanghai Municipality(20ZR1448500)

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Abstract

Bipolar disorder, as a major mental illness, has a high lifetime suicide attempt rate in patients, and suicidal behavior is most likely to occur during depressive episodes. Therefore, in-depth study of its mechanism is essential for prevention, early detection and intervention of suicide. With the development of magnetic resonance imaging (MRI) technology, it has been found that there are abnormalities in the brain structure and function in suicidal patients with bipolar disorder. This article reviews the studies on suicide in bipolar disorder patients by MRI from four aspects: structure, function, structure-function, and central metabolism and cerebral blood flow perfusion, and summarizes the suicide-related changes. This review focuses on distinguishing the brain MRI changes under different mood states and diverse definitions of suicide, aiming to provide reference for further exploration of the pathophysiological mechanism of suicide in bipolar disorder.

Key words： bipolar disorder; suicidal ideation; suicidal attempt; magnetic resonance imaging (MRI); brain

Cite this article

Jiaye CHEN , Huifeng ZHANG , Wenxian LU , Daihui PENG . Research progress of brain magnetic resonance imaging related to suicide in bipolar disorder patients[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2023 , 43(7) : 939 -944 . DOI: 10.3969/j.issn.1674-8115.2023.07.017

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