Journal of Shanghai Jiao Tong University (Medical Science) >

2024 , Vol. 44 >Issue 1: 72 - 78

DOI: https://doi.org/10.3969/j.issn.1674-8115.2024.01.008

Clinical research

Correlation between body compositions and cardiopulmonary fitness in patients with coronary heart disease

  • Yang LI ,
  • Jun MA ,
  • Yihong DU ,
  • Li XU ,
  • Hanfen CHEN ,
  • Xunhan QIU ,
  • Meng JIANG ,
  • Jun PU
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  • Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
PU Jun, E-mail: pujun310@hotmail.com.
JIANG Meng, E-mail: jiangmen90919@163.com

Received date: 2023-05-30

  Accepted date: 2023-12-05

  Online published: 2024-01-28

Supported by

National Natural Science Foundation Joint Fund Project(U21A20341);National Natural Science Foundation of China(81971570);Medical Innovation Research Special Project of "Science and Technology Innovation Action Plan" in Shanghai(20Y11910500);Excellent Technology Leader Program Project of "Science and Technology Innovation Action Plan" in Shanghai(21XD1432100);"Two-hundred Talents" Program of Shanghai Jiao Tong University School of Medicine(20172014)

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Abstract

Objective ·To explore the correlation between body compositions and cardiovascular fitness (CRF) in patients with coronary heart disease (CHD). Methods ·The CHD patients (CHD group) who underwent elective percutaneous coronary intervention treatment at Renji Hospital, Shanghai Jiao Tong University School of Medicine from October 2022 to June 2023 as well as healthy people (control group) were selected. All the participants completed cardiopulmonary exercise testing (CPET) to determine CRF and bioelectrical impedance analysis (BIA) to determine body compositions on the same day. Results ·A total of 191 patients with coronary heart disease and 188 healthy individuals were included. There was no statistically significant difference in baseline characteristics between the two groups. Compared with the control group, the CRF indicators of the CHD group were significantly reduced (all P<0.05). In terms of body composition indicators, the trunk muscle mass (TMM) of the CHD group was significantly lower than that of the control group (P<0.01), and the trunk fat mass (TFM) was significantly higher than that of the control group (P<0.01). Correlation analysis showed that TMM (R=0.538), lower limbs muscle mass (LMM) (R=0.754), and lower limbs fat mass (LFM) (R=0.593) were positively correlated with peak oxygen uptake per kilogram of bodyweight (VO2peak/kg) in the CHD group (all P<0.01), while TFM (R=-0.563) was negatively correlated with VO2peak/kg (P<0.01). There was no statistically significant correlation between other body composition indicators and VO2peak/kg. According to VO2peak/kg, the CHD patients were divided into low CRF group, medium CRF group, and high CRF group. The results showed that there were statistically significant differences in LMM, TMM, LFM, and TFM among the three groups of patients (all P<0.05). Multiple linear regression analysis suggested that age, gender, TMM, TFM, LMM, and LFM were related factors of VO2peak/kg in the patients with CHD. The VO2peak/kg of CHD patients increased with the increase of TMM, LMM, and LFM and the decrease of age and TFM; the female patients had lower VO2peak/kg compared to the males. Conclusion ·The CRF of CHD patients is significantly lower than that of the healthy population, with higher TFM and lower TMM; in the CHD patients, CRF is negatively correlated with TFM and positively correlated with TMM, LMM, and LFM.

Key words： coronary heart disease (CHD); cardiopulmonary fitness (CRF); body composition

Cite this article

Yang LI , Jun MA , Yihong DU , Li XU , Hanfen CHEN , Xunhan QIU , Meng JIANG , Jun PU . Correlation between body compositions and cardiopulmonary fitness in patients with coronary heart disease[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2024 , 44(1) : 72 -78 . DOI: 10.3969/j.issn.1674-8115.2024.01.008

References

1 马丽媛, 王增武, 樊静, 等. 《中国心血管健康与疾病报告2021》概要[J]. 中国介入心脏病学杂志, 2022, 30(7): 481-496.
1 MA L Y, WANG Z W, FAN J, et al. Summary of Report on cardiovascular health and diseases in China 2021[J]. Chinese Journal of Interventional Cardiology, 2022, 30(7): 481-496.
2 POWELL-WILEY T M, POIRIER P, BURKE L E, et al. Obesity and cardiovascular disease: a scientific statement from the American Heart Association[J]. Circulation, 2021, 143(21): e984-e1010.
3 HARADA H, KAI H, NIIYAMA H, et al. Effectiveness of cardiac rehabilitation for prevention and treatment of sarcopenia in patients with cardiovascular disease: a retrospective cross-sectional analysis[J]. J Nutr Health Aging, 2017, 21(4): 449-456.
4 NICHOLS S, O′DOHERTY A F, TAYLOR C, et al. Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease: a CARE CR study[J]. Clin Physiol Funct Imaging, 2019, 39(1): 93-102.
5 ROSS R, BLAIR S N, ARENA R, et al. Importance of assessing cardiorespiratory fitness in clinical practice: a case for fitness as a clinical vital sign: a scientific statement from the American Heart Association[J]. Circulation, 2016, 134(24): e653-e699.
6 ARNETT D K, BLUMENTHAL R S, ALBERT M A, et al. 2019 ACC/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines[J]. Circulation, 2019, 140(11): e596-e646.
7 GUAZZI M, ADAMS V, CONRAADS V, et al. EACPR/AHA Scientific Statement. Clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations[J]. Circulation, 2012, 126(18): 2261-2274.
8 LAWTON J S, TAMIS-HOLLAND J E, BANGALORE S, et al. 2021 ACC/AHA/SCAI guideline for coronary artery revascularization: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines[J]. J Am Coll Cardiol, 2022, 79(2): 197-215.
9 GRUNDY S M, STONE N J, BAILEY A L, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines[J]. Circulation, 2019, 139(25): e1082-e1143.
10 FLACK J M, ADEKOLA B. Blood pressure and the new ACC/AHA hypertension guidelines[J]. Trends Cardiovasc Med, 2020, 30(3): 160-164.
11 PALANGE P, WARD S A, Carlsen K-H, et al. Recommendations on the use of exercise testing in clinical practice[J]. Eur Respir J, 2007, 29(1): 185-209.
12 JUNG S, PARK J, SEO Y G. Relationship between arm-to-leg and limbs-to-trunk body composition ratio and cardiovascular disease risk factors[J]. Sci Rep, 2021, 11(1): 17414.
13 STICKLAND M K, NEDER J A, GUENETTE J A, et al. Using cardiopulmonary exercise testing to understand dyspnea and exercise intolerance in respiratory disease[J]. Chest, 2022, 161(6): 1505-1516.
14 MYERS J, KAMINSKY L A, LIMA R, et al. A reference equation for normal standards for VO2 max: analysis from the fitness registry and the importance of exercise national database (FRIEND registry)[J]. Prog Cardiovasc Dis, 2017, 60(1): 21-29.
15 LEE D C, SUI X M, ARTERO E G, et al. Long-term effects of changes in cardiorespiratory fitness and body mass index on all-cause and cardiovascular disease mortality in men: the Aerobics Center Longitudinal Study[J]. Circulation, 2011, 124(23): 2483-2490.
16 AL-MALLAH M H, SAKR S, AL-QUNAIBET A. Cardiorespiratory fitness and cardiovascular disease prevention: an update[J]. Curr Atheroscler Rep, 2018, 20(1): 1.
17 FLEGAL K M, KIT B K, ORPANA H, et al. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis[J]. JAMA, 2013, 309(1): 71-82.
18 ELAGIZI A, KACHUR S, LAVIE C J, et al. An overview and update on obesity and the obesity paradox in cardiovascular diseases[J]. Prog Cardiovasc Dis, 2018, 61(2): 142-150.
19 HURT R T, EBBERT J O, CROGHAN I, et al. The comparison of segmental multifrequency bioelectrical impedance analysis and dual-energy X-ray absorptiometry for estimating fat free mass and percentage body fat in an ambulatory population[J]. JPEN J Parenter Enteral Nutr, 2021, 45(6): 1231-1238.
20 KATTA N, LOETHEN T, LAVIE C J, et al. Obesity and coronary heart disease: epidemiology, pathology, and coronary artery imaging[J]. Curr Probl Cardiol, 2021, 46(3): 100655.
21 ZHOU H Y, XIE G, LUO L Y, et al. Age- and sex-related trends in body composition among Beijing adults aged 20?60 years: a cross-sectional study[J]. BMC Public Health, 2023, 23(1): 1519.
22 WU C C, BU R S, WANG Y G, et al. Rehabilitation effects of circuit resistance training in coronary heart disease patients: a systematic review and meta-analysis[J]. Clin Cardiol, 2022, 45(8): 821-830.
23 BLüHER M. Metabolically healthy obesity[J]. Endocr Rev, 2020, 41(3): bnaa004.
24 CHEN G C, ARTHUR R, IYENGAR N M, et al. Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index[J]. Eur Heart J, 2019, 40(34): 2849-2855.
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