Objective To explore the effects of clinical skill training in post-graduates with clinical speciality degree. Methods One hundred post-graduates with clinical speciality degree in Shanghai Chest Hospital were randomly divided into two groups, with 50 post-graduates in each group. One group of post-graduates were managed with residents' training, while the other with traditional clinical training. Clinical skills were compared between two groups before and after training by examinations. The knowledge and idea of residents' training were obtained from 200 residents and instructors through questionnaire survey. Results It was revealed by the examinations that the scores of comprehensive theory and clinical skills in post-graduates with residents' training were significantly higher than those in postgraduates with traditional clinical training [（90.53±3.17） vs （80.23±4.42） and （89.46±3.78） vs （80.50±4.16），P<0.001 for both]. However, there was no significant difference in scores of major English ability and profession morals between two groups [（90.43±3.18） vs （90.58±3.43) and （89.06±3.57） vs （90.47±3.15），P>0.05 for both]. The questionnaire survey indicated that most post-graduates considered residents' training could improve the clinical skills. Conclusion Residents' training is helpful to improve the clinical skills for postgraduates with clinical speciality degree.