Research progress of regulation of osteoblast differentiation and proliferation
Online published: 2011-10-27
During bone metabolism and bone remodeling, mesenchymal cells differentiate into osteoblasts under certain conditions, which play an important role in bone formation. The normal bone remodeling and part of the bone pathological changes are closely related to osteoblast differentiation and proliferation. Osteoblast differentiation and proliferation are regulated by a variety of systemic and regional factors. Recent progress of regulation of osteoblast differentiation and proliferation is reviewed in this paper.
Key words: osteoblast; differentiation; proliferation; regulation
WANG Yong-ping, OUYANG Yuan-ming, JIANG Yao . Research progress of regulation of osteoblast differentiation and proliferation[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2011 , 31(10) : 1465 . DOI: 10.3969/j.issn.1674-8115.2011.10.024
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