Original article (Clinical research)

Role of 18F-FDG PET/CT whole body scan in diagnosis of small bowel tumors

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  • 1.Department of Nuclear Medicine, 2.Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China

Online published: 2012-06-01

Supported by

Shanghai Leading Academic Discipline Project, S30203;Shanghai Research Foundation for Cultivation of Outstanding Young Teachers in Colleges, jdy09096

Abstract

Objective To investigate the value of 18F-FDG PET/CT whole body scan in the diagnosis of small bowel tumors. Methods The clinical data of 24 patients who had undergone 18F-FDG PET/CT whole body scan and were highly suspected with small bowel tumors were retrospectively analysed, and comparison analysis was conducted between results of PET/CT examinations and findings of double-balloon small bowel endoscopy, biopsy and surgical pathology. Results The data of 2 patients with extra-intestinal malignant tumors confirmed by pathology were excluded. Among the 22 patients with small bowel tumors, 16 patients were diagnosed as small bowel malignant tumors by 18F-FDG PET/CT whole body scan (17 small bowel malignant tumor lesions and 27 involved lymph nodes), 4 patients were diagnosed as small bowel benign tumors and benign lesions, 1 patient with intestinal tuberculosis had false positive PET/CT findings, and 1 patient with small intestinal signet ring cell carcinoma had false negative PET/CT findings. The sensitivity and specificity of 18F-FDG PET/CT in diagnosis of small bowel malignant tumors were 94.12% and 80.00% respectively, and the positive predictive value, negative predictive value and accuracy in diagnosis were 94.12%, 80.00% and 90.91% respectively. Conclusion 18F-FDG PET/CT whole body scan is a feasible, safe, noninvasive and promising diagnostic tool for detecting small bowel malignancies, differentiating benign and malignant tumors, staging and guiding clinical treatment.

Cite this article

HU Jia-jia, WANG Zheng-ting, ZHONG Jie, et al . Role of 18F-FDG PET/CT whole body scan in diagnosis of small bowel tumors[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2012 , 32(5) : 610 . DOI: 10.3969/j.issn.1674-8115.2012.05.017

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