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Research progress of high throughput drug screening models

XU Yuan-yuan1, CHEN Peng-hui1, WU Ying-li2   

  1. 1.Grade 2009 of 5-year Clinical Medicine Program, 2.Key Laboratory of Cell Differentiation and Apoptosis of National Ministry of Education, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2013-10-28 Published:2013-10-31

Abstract:

As the core of high throughput screening systems, screening models have enjoyed remarkable development and wider application driven by intensive studies and technology advancement. Discussed in this paper are the latest progress in molecule, cell and animal based models of high throughput screening and their recent applications in drug screening, as well as their pros and cons and related theories.

Key words: high throughput screening, drug screening, models