›› 2018, Vol. 38 ›› Issue (9): 1128-.doi: 10.3969/j.issn.1674-8115.2018.09.021

• Review • Previous Articles     Next Articles

Application of mechanical thrombectomy in the patients with wake-up stroke

HU Yue, HE Xin-wei, LIU Yi-sheng, ZHAO Rong, LIU Jian-ren   

  1. Department of Neurology, Stroke Center, Shanghai Ninth Peoples Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
  • Online:2018-09-28 Published:2018-10-15
  • Supported by:
    Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Support, 20161422; Clinical Research Project of Shanghai Jiao Tong University School of Medicine, DLY201614; Key Biological and Pharmaceutical Project of Shanghai Municipal Science and Technology Commission, 16411953100

Abstract: Wake-up stroke (WUS), which is characterizedthe uncertain onset time and poor short-term outcome, accounts for 25% of stroke. Due to the above two points, how to choose the treatment methods remains to be researched. The mechanical thrombectomy is the first-line treatment of acute ischemic stroke (AIS). DAWN and DEFUSE-3 studies have recently demonstrated that the treatment window can be expanded to 24 hours, so the endovascular treatment may be effective and safe in some WUS patients according to the existence of “the mismatch of clinical score and imaging infart core”CT perfusion imaging and other modern imaging methods. This article summarized the application of mechanical thrombectomy in WUS treatment in recent years.

Key words: wake-up stroke, acute ischemic stroke, mechanical thrombectomy, cerebral perfusion imaging

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