JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (8): 1129-1132.doi: 10.3969/j.issn.1674-8115.2021.08.023

• Case report • Previous Articles    

A case report of Peutz-Jeghers syndrome with jejunal intussusception

Ming-wang LUO1(), Zhao-qi ZHANG2(), Yuan WEI1, Wen-di YAN3, Dong-wang YAN2()   

  1. 1.Department of General Surgery, Pangang Xichang Hospital, Liangshan Yi Autonomous Prefecture of Sichuan Province, Xichang 615012, China
    2.Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
    3.Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
  • Online:2021-08-28 Published:2021-07-28
  • Contact: Dong-wang YAN;
  • Supported by:
    National Natural Science Foundation of China(81871931)


A female patient, 16-year-old, presented ??recurrent lower abdominal pain for one year, recurrence and aggravation for 10 days''. Physical examination revealed that the patient's lips had dot-like dark spots, 1?4 mm in diameter, with clear boundaries and without fusion and fading under pressure, and there was tenderness in the upper left abdomen. The laboratory and imaging examinations were further completed and the patient was admitted to hospital with ??1. intussusception; 2. multiple polyps in the intestine; 3. likely Peutz-Jeghers syndrome (PJS)''. After admission, laparotomy was performed for duodenal and jejunal polyp resection, and the postoperative diagnosis was PJS. PJS is a clinically rare disease with three typical characteristics: skin and mucous membrane pigmentation, multiple polyps in the gastrointestinal tract, and family genetic tendency. The clinical data of this case are introduced to improve the understanding of PJS, provide reference for the following diagnosis and treatment of similar patients, and reduce the occurrence of emergency surgery and short bowel syndrome.

Key words: Peutz-Jeghers syndrome (PJS), intussusception, familial adenomatous polyposis

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