Abstract:

Objective ·To investigate the anesthetic effect of PetCO₂ monitoring nasopharyngeal airway on preventing hypoxia in patients with obstructive sleep apnea syndrome (OSAS) during magnifying endoscopy. Methods ·Eighty OSAS patients who underwent magnifying endoscopy anesthesia in Xuchang Central Hospital of Henan Province from February to June 2023 were randomly divided into PetCO₂ monitoring nasopharyngeal airway group (group T) and traditional nasopharyngeal airway group (group B), with 40 cases in each group. General information, perioperative data and total anesthetic dosage of the two groups of patients were collected and compared. The systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and pulse oxygen saturation (SpO₂) of the two groups of patients before anesthesia (T0), at the time of entering the endoscopy (T1), 3 min after entering the endoscopy (T2), 10 min after entering the endoscopy (T3) and at the end of endoscopy (T4) were observed and recorded, respectively. The incidence of body movement and hypoxemia, and the effects of preventing hypoxia (including mask ventilation, jaw-lift support and chest compressions to assist breath) of the two groups of patients were recorded. Results ·There were no significant differences in general information, perioperative data and total anesthetic dosage between the two groups. At T1 and T2, SpO₂ in group T was higher than that in group B (T1: P=0.041,T2: P=0.012), and there was no statistically significant difference in SBP, DBP and HR between the groups; at other time points, there was no statistically significant difference in the four indicators between the two groups. Compared with group B, the incidences of body movement, hypoxemia, mask ventilation, jaw-lift support and chest compressions to assist breath in group T were all decreased (all P=0.000). Conclusion ·PetCO₂ monitoring nasopharyngeal airway can reduce the incidence of hypoxia during magnifying endoscopy in patients with OSAS, with minimal adverse events. Also, it can detect the status of lung ventilation in time, guide clinical intervention, reduce complications and improve the safety of magnifying endoscopy anesthesia.

Key words: PetCO₂ monitoring nasopharyngeal airway, magnifying endoscopy, obstructive sleep apnea syndrome (OSAS), hypoxemia, anesthesia safety