Journal of Shanghai Jiao Tong University (Medical Science) ›› 2024, Vol. 44 ›› Issue (2): 287-290.doi: 10.3969/j.issn.1674-8115.2024.02.016

• Case report • Previous Articles    

A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia

LIU Jiayu(), HUANG Fang(), HAO Siguo()   

  1. Department of Hematology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200082, China
  • Received:2023-10-09 Accepted:2023-12-07 Online:2024-02-28 Published:2024-03-25
  • Contact: HUANG Fang,HAO Siguo E-mail:Liu_jiayu@139.com;huangfang335@163.com;huangfang01@xinhuamed.com.cn;haosiguo@xinhuamed.com.cn

Abstract:

Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 monoclonal antibody), and hetrombopag. The coexistence mechanism of CMML and ITP needs to be further clarified. Venetoclax combined with anti-CD20 monoclonal antibody and thrombopoietin receptor agonist may be an effective strategy for the treatment of this complication.

Key words: chronic myelomonocytic leukemia, immune thrombocytopenia, venetoclax, hetrombopag, ripertamab

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