Abstract:

Objective To observe the therapeutic effect of vacuum sealing drainage in severe burns with the systemic inflammatory response syndrome (SIRS). Methods A total of 36 cases of severe burn combined with SIRS were divided into treatment group (n=18) and control group (n=18). Vacuum sealing drainage was used for treatment group while the sulfadiazine silver was used for the control group. The incidence of complications, exudation of 1% total body surface area (TBSA), cost of hospitalization, use of human serum albumin and red blood cell of each group were compared within 7 d after surgery. The leucocyte count, percentage of neutrophile granulocyte, C reactive protein (CRP) and procalcitonin (PCT) were compared between two groups before surgery and at 24, 72, and 120 h after surgery. Results The incidence of complications of treatment group was less than the control group after surgery (P<0.05). The cost of 1% TBSA hospitalization, consumption of red blood cell and human serum albumin, and exudation within 7 d after surgery were all significantly lower than those of control group, the difference was statistically significant (P<0.05). The leucocyte count, percentage of neutrophile granulocyte, CRP, and PCT after surgery being performed 24 h were all significantly lower than those of control group, the difference was statistically significant (P<0.05). Conclusion Vacuum sealing drainage is an efficient method to treat severe burn combined with SIRS. It can reduce the incidence rate of sepsis and other complications and cost of hospitalization.

Key words: severe burn, systemic inflammatory response syndrome, vacuum sealing drainage