Abstract:

Objective To analyze the cost-effectiveness of intensive treatments for inpatients with noninsulin-dependent diabetes mellitus of a grade A tertiary hospital in Xinjiang and explore the effectiveness and economy of continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI). Methods The prevalence survey was adopted and the cost-effectiveness of two intensive treatments was compared by the cost-effectiveness ratio and sensitivity analysis. Results The unit costs of CSII group and MDI group were 6 215.59 yuan and 5 809.14 yuan, respectively. For effectively treated cases, the costs of CSII group and MDI group for patients to achieve the normal blood glucose level 1 d earlier were 2 972.67 yuan and 4 224.83 yuan; the costs for effective rate to increase one percent were 227.36 yuan and 929.46 yuan; and the costs for average blood glucose level to decrease 1 mmol/L on the day that the normal blood glucose level was achieved were 1 246.40 yuan and 2 643.53 yuan. The results of sensitivity analysis were consistent with that of the cost-effectiveness ratio analysis, which showed that the results of cost-effectiveness analysis were stable and reliable. Conclusion The effects of CSII treatment are better than those of the MDI treatment. CSII treatment is an effective, reasonable, and economic treatment.

Key words: noninsulin-dependent diabetes mellitus, insulin, intensive therapy, cost-effectiveness analysis