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Evaluation of the application of hybrid iterative reconstruction method (iDOSE4) to low-dose chest scan with 256 slices computed tomography

WANG Bo-cheng, XUE yang, SU xiao, MEI Yun-ting, WU Li-zhong, ZHAO Jiang-ming   

  1. Department of Radiology, Shanghai Ninth People’s Hospital,  Shanghai Jiao Tong University School of Medicine， Shanghai 201999, China
  • Online:2016-05-28 Published:2016-05-26
  • Supported by:

    Shanghai Municipal Science and technology innovation action plan，10411953400；Project of Shanghai health and Family Planning Commission，20124194; Scientific research project of Science and Technology Committee of  Baoshan District Shanghai， 14-E-4

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Abstract:

Objective To compare the quality of chest images scanned by iCT with low radiation dose and with regular radiation dose and by CT with regular radiation dose, and explore the application value of iDOSE4 in low radiation dose scan. Methods Chest spiral CT scan images of 150 healthy males without chest disorders were enrolled and randomly assigned to the 256 slices iDOSE4 low-dose group (iDOSE4 low dose group, n=50), 256 slices iDOSE4 regular dose group (iDOSE4 regular dose group, n=50), and 64 rows regular dose group (n=50). The quality of CT images (lung markings, mediastinum artery outline, bronchial morphology, and axillary lymph nodes) was scored, compared, and analyzed. Results The differences in lung markings, mediastinum artery outline, and bronchial morphology scores between the iDOSE4 low dose group and the iDOSE4 regular dose group were not statistically significant (P=0.633, P=0.814, P=0.543). Axillary lymph nodes score and the total score in the iDOSE4 low dose group were lower as compared with the iDOSE4 regular dose group (P=0.000, P=0.000). The differences in lung markings, mediastinum artery outline, and bronchial morphology scores between the iDOSE4 low dose group and the 64 rows regular dose group were not statistically significant (P=0.466, P=0.820, P=0.377). Axillary lymph nodes score and the total score in the iDOSE4 low dose group were lower as compared with the 64 rows regular dose group (P=0.000, P=0.000). There was no significant difference in the quality of CT images between the iDOSE4 regular dose group and the 64 rows regular dose group. The 64 rows regular dose group had the highest radiation dose (13.6 mGy), followed by the iDOSE4 regular dose group (9.7mGy) and the iDOSE4 low dose group (3.4 mGy). Conclusion The 256 slices low-dose chest CT scan with iDOSE4 method can obtain images with reliable quality and can significantly reduce the radiation dose with only inferior capability for displaying axillary lymph nodes as compared with the regular dose.

Key words: computed tomography, low dose, image quality, chest