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Research progress of magnetic resonance technology in investigating the role of cerebellar in the pathophysiology of obsessive-compulsive disorder

XU Ting-ting, WANG Zhen   

  1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2017-05-28 Published:2017-05-31
  • Supported by:

    National Natural Science Foundation of China, 81671340; Biomedical Engineering Cross Research Foundation of Shanghai Jiao Tong University, YG2013MS65


Obsessive-compulsive disorder (OCD) is a chronic disabling mental illness with the core symptoms of obsession and compulsion, while its pathological mechanism has not yet been fully understood. In recent years, magnetic resonance (MR) technology has been used in the study of mental illness, because of its nonradiative and non-invasive advantage, etc. Many MR studies have found that OCD patients have cerebellar changes in structure and function, and these changes have contact with the incidence of OCD. This paper reviews the cerebellar’s role in the onset of OCD applying MR technology.

Key words: obsessive compulsive disorder, cerebellum, magnetic resonance, diffusion tensor image