Abstract:

 Objective · To compare the impacts on clinical efficiency and safety between 0.014 inch Synchro microwire and Transend microwire used during mechanical thrombectomy for acute ischemic stroke (AIS) caused by large artery occlusion.  Methods · Forty-six patients undergoing mechanical thrombectomy with stent retrievers between October 2012 and January 2016 were included, who were classified into Synchro group (21 cases) and Transend group (25 cases). The clinical outcome, procedure time, and safety were analyzed and compared between two groups.  Results · The recanalization rates were similar between two groups (P=0.600) , but time from puncture to vascular recanalization of Synchro group was much shorter than that of Transend goup (48.88 min vs 82.33 min, P=0.001). The rates of functional independence (modified Rankin scale score ≤ 2) were similar between two groups (P=1.000). There was no significant difference of the rates of post-procedure subarachnoid hemorrhage (PSAH) between two groups (P=1.000). However, there were two cases that had fatal subarachnoid hemorrhage with intracranial hematoma in Transend group, while there was only one case of mild subarachnoid hemorrhage who recovered well in Synchro group.  Conclusion · Compared with Transend microwire, Synchro microwire can significantly shorten the procedure time of mechanical thrombectomy, and the risk of fatal subarachnoid hemorrhage is rather small.

Key words:  mechanical thrombectomy, Synchro microwire, Transend microwire, acute ischemic stroke, post-procedure subarachnoid hemorrhage, intracranial artery perforation