›› 2017, Vol. 37 ›› Issue (12): 1670-.doi: 10.3969/j.issn.1674-8115.2017.12.016

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Clinical and pathological characteristics of endometrial carcinoma in premenopausal and  postmenopausal patients#br#

LIU Hua, JIAN Fang-fang, SONG Wei, SHEN Li-fei   

  1. Department of Obstetrics and Gynecology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Online:2017-12-28 Published:2018-01-10

Abstract: Objective · To analyze the clinical and pathological characteristics of endometrial carcinoma patients before and after menopause.  Methods · Fifty-two premenopausal cases and 150 postmenopausal cases with endometrial carcinoma from December 2013 to March 2017 in Ruijin Hospital, Shanghai Jiao Tong University School of Medicine were retrospectively analyzed.   Results · The ratio of patients with hypertension in premenopausal group was 28.8%, which was significantly lower than that in postmenopausal group (P<0.01). In premenopausal group, the proportion of G3 in histological grading was 8.3%, and the ratio of deep myometrial invasion was 13.5%, all of which were significantly lower than those of postmenopausal group (P<0.05). The ratio of ovarian involvement was as high as 17.6%, which was significantly higher than that of postmenopausal group (P<0.05). There were no significant differences between the two groups in other clinical-pathological parameters such as obesity, diabetes, CA125, CA199, surgical-pathological staging, pathological type, vascular involvement, and lymph node metastasis.  Conclusion · Premenopausal endometrial carcinoma is less malignant, while the probability of ovarian involvement is higher.

Key words: endometrial carcinoma, premenopause, postmenopause, clinical-pathological characteristic