JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (5): 612-616.doi: 10.3969/j.issn.1674-8115.2021.05.008
• Clinical research • Previous Articles Next Articles
Xu-guang CHEN(), Sheng-yi SHI, Lan HU, Yu CHEN, Yi-ming LU, Jing YE(
)
Online:
2021-05-28
Published:
2021-05-27
Contact:
Jing YE
E-mail:johncxg@126.com;carlionje8@126.com
Supported by:
CLC Number:
Xu-guang CHEN, Sheng-yi SHI, Lan HU, Yu CHEN, Yi-ming LU, Jing YE. Evaluative value of plasma fibrin degradation product in early prognosis of patients with hemorrhagic stroke[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(5): 612-616.
Index | Total (n=606) | Death group (n=85) | Survival group (n=521) | P value① |
---|---|---|---|---|
Age/year | 58.9±15.1 | 63.6±15.6 | 58.0±14.8 | 0.001 |
Male/n (%) | 405 (66.8) | 58 (68.2) | 347 (66.6) | 0.767 |
GCS score/score | 11 (8,13) | 7 (5,10) | 12 (9,13) | 0.000 |
SBP/mmHg② | 169±23 | 173±37 | 168±26 | 0.117 |
DBP/mmHg | 96±16 | 98±19 | 96±15 | 0.264 |
Midline displacement/n (%) | 127 (21.0) | 49 (57.6) | 78 (15.0) | 0.000 |
Receive surgery/n (%) | 124 (20.5) | 27 (31.8) | 97 (18.6) | 0.005 |
Type of hemorrhage/n (%) | 0.810 | |||
ICH | 493 (81.4) | 67 (78.8) | 426 (81.8) | |
PIVH | 32 (5.3) | 5 (5.9) | 27 (5.2) | |
SAH | 81 (13.4) | 13 (15.3) | 68 (13.1) | |
FDP/(μg·mL-1) | 1.19 (0.70, 2.71) | 2.07 (0.92, 5.65) | 1.12 (0.70, 2.23) | 0.000 |
Glu/(mmol·L-1) | 8.4±2.9 | 10.5±3.5 | 8.1±2.6 | 0.000 |
Ca/(mmol·L-1) | 2.3±0.1 | 2.3±0.1 | 2.3±0.1 | 0.951 |
WBC/(×109·L-1) | 9.4±3.9 | 12.1±4.9 | 9.0±3.5 | 0.000 |
PLT/(×109·L-1) | 193±61 | 196±73 | 192±58 | 0.623 |
INR | 1.05±0.3 | 1.03±0.19 | 1.06±0.32 | 0.471 |
Cr/(μmol·L-1) | 87±56 | 93±55 | 86±56 | 0.404 |
GPT/(U·L-1) | 22±19 | 21±13 | 22±20 | 0.606 |
cTnI/(ng·mL-1) | 0.03±0.08 | 0.03±0.05 | 0.03±0.08 | 0.869 |
CRP/(mg·L-1) | 12±15 | 16±28 | 11±12 | 0.230 |
Tab 1 Comparison of baseline clinical characteristics between surviving and dead patients within 14 d after onset
Index | Total (n=606) | Death group (n=85) | Survival group (n=521) | P value① |
---|---|---|---|---|
Age/year | 58.9±15.1 | 63.6±15.6 | 58.0±14.8 | 0.001 |
Male/n (%) | 405 (66.8) | 58 (68.2) | 347 (66.6) | 0.767 |
GCS score/score | 11 (8,13) | 7 (5,10) | 12 (9,13) | 0.000 |
SBP/mmHg② | 169±23 | 173±37 | 168±26 | 0.117 |
DBP/mmHg | 96±16 | 98±19 | 96±15 | 0.264 |
Midline displacement/n (%) | 127 (21.0) | 49 (57.6) | 78 (15.0) | 0.000 |
Receive surgery/n (%) | 124 (20.5) | 27 (31.8) | 97 (18.6) | 0.005 |
Type of hemorrhage/n (%) | 0.810 | |||
ICH | 493 (81.4) | 67 (78.8) | 426 (81.8) | |
PIVH | 32 (5.3) | 5 (5.9) | 27 (5.2) | |
SAH | 81 (13.4) | 13 (15.3) | 68 (13.1) | |
FDP/(μg·mL-1) | 1.19 (0.70, 2.71) | 2.07 (0.92, 5.65) | 1.12 (0.70, 2.23) | 0.000 |
Glu/(mmol·L-1) | 8.4±2.9 | 10.5±3.5 | 8.1±2.6 | 0.000 |
Ca/(mmol·L-1) | 2.3±0.1 | 2.3±0.1 | 2.3±0.1 | 0.951 |
WBC/(×109·L-1) | 9.4±3.9 | 12.1±4.9 | 9.0±3.5 | 0.000 |
PLT/(×109·L-1) | 193±61 | 196±73 | 192±58 | 0.623 |
INR | 1.05±0.3 | 1.03±0.19 | 1.06±0.32 | 0.471 |
Cr/(μmol·L-1) | 87±56 | 93±55 | 86±56 | 0.404 |
GPT/(U·L-1) | 22±19 | 21±13 | 22±20 | 0.606 |
cTnI/(ng·mL-1) | 0.03±0.08 | 0.03±0.05 | 0.03±0.08 | 0.869 |
CRP/(mg·L-1) | 12±15 | 16±28 | 11±12 | 0.230 |
Factor | OR (95%CI) | P value |
---|---|---|
Midline displacement | 3.149 (1.861?5.462) | 0.000 |
FDP>2.78 μg·mL-1 | 2.564 (1.490?4.413) | 0.001 |
GCS score<11 score | 3.779 (2.075?6.880) | 0.000 |
Age>64 year | 1.777 (1.047?3.015) | 0.033 |
Glu>8.7 mmol·L-1 | 2.140 (1.284?3.568) | 0.004 |
Tab 2 Multivariate Logistic regression analysis of risk factors for death within 14 d of HS patients
Factor | OR (95%CI) | P value |
---|---|---|
Midline displacement | 3.149 (1.861?5.462) | 0.000 |
FDP>2.78 μg·mL-1 | 2.564 (1.490?4.413) | 0.001 |
GCS score<11 score | 3.779 (2.075?6.880) | 0.000 |
Age>64 year | 1.777 (1.047?3.015) | 0.033 |
Glu>8.7 mmol·L-1 | 2.140 (1.284?3.568) | 0.004 |
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