Abstract:

Objective To investigate the therapeutic effects of regimen designed by Chinese Center for Disease Control and Prevention (conventional regimen) on patients with single gonococcal infection or with infections of gonococci mixed with other pathogens. Methods The clinical data of 32 patients with single gonococcal infection and 50 patients with gonococcal infection mixed with the other pathogen infection (gonococcal infection mixed with Chlamydia trachomatis infection, mycoplasma urealytium infection or treponema pallidum infection) were collected, the therapeutic effects of conventional regimen were retrospectively analysed, and time spent for clinical recovery (from the initiation of conventional regimen to clinical recovery) was compared between patients with single gonococcal infection and those with gonococcal infection mixed with the other pathogen infection. Results The total clinical recovery rate was 92.4%, with 100% for patients with single gonococcal infection and 84.0% for those with gonococcal infection mixed with the other pathogen infection. Time spent for clinical recovery for patients with single gonococcal infection and those with gonococcal infection mixed with the other pathogen infection was (9.4±1.8) d and (9.7±2.3) d, respectively, and there was no significant difference between them (P>0.05). Conclusion Time spent for clinical recovery for patients with gonococcal infection mixed with the other pathogen is similar to that for patients with single gonococcal infection, indicating that conventional regimen is also suitable to patients with gonococcal infection mixed with the other pathogen infection.

Key words: gonorrhea, mixed infection, Chlamydia trachomatis, mycoplasma urealytium, treponema pallidum