Abstract:

Objective With invasive coronary angiography (ICA) as the golden standard for diagnosis, to explore the sensitivity and specificity of dual-source computed tomography (DSCT) in the diagnosis of coronary artery stenosis and to confirm DSCT feasibility in screening coronary artery disease (CAD). Methods A total of 200 cases of suspected CAD, including 30 cases of arrhythmia, were retrospectively analyzed. The patients underwent DSCT and ICA in turn with the interval time between the two tests less than 3 months. ICA, as the golden standard for diagnosis, was used to evaluate the value of DSCT in the diagnosis of CAD. Results Among 200 patients, 158 were diagnosed as coronary stenosis (luminal stenosis≥50%) by ICA, while 161, as coronary stenosis by DSCT. The sensitivity and specificity of DSCT were 98.1% (155/158) and 85.7% (36/42). Among 2000 coronary segments, 326 were diagnosed as stenosis (luminal stenosis≥50%), while 326, also diagnosed as stenosis by DSCT (P>0.05). The sensitivity and specificity of DSCT were 96.3% (314/326) and 99.3% (1662/1674), respectively. Furthermore, the negative predictive value of DSCT was more than 99%. Conclusion DSCT, with good sensitivity, specificity, and negative predictive value, can be applied to screen CAD in more people, especially for those coronary stenosis without calcification.

Key words: dual-source computed tomography, invasive coronary angiography, retrospective