›› 2013, Vol. 33 ›› Issue (4): 510-.doi: 10.3969/j.issn.1674-8115.2013.04.028

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MicroRNA—new approach to diagnosis, treatment and prognosis prediction of breast cancer

DU Wei1, HUO Zi-rong1, LIANG Cheng-cai1, TAO Shi-cong1, SUN Yue-ping2   

  1. 1.Grade 2009 of the 8-year Medical Education Program, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; 2.Department of Biochemitstry and Molecular Cell Biology, Basic Medical College Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2013-04-28 Published:2013-05-03


MicroRNA (miRNA) is a small and non-coding RNA that regulates gene expression at the post-transcriptional level, affecting on almost all the cellular processes. Recent studies have revealed the important role of miRNA in the tumorigenesis and development of breast cancer, indicating a new hope for its diagnosis, treatment and prognosis prediction. The latest progress in miRNA studies on breast cancer is introduced in this paper, and the potential application of miRNA is analysed.

Key words: breast cancer, MiRNA, diagnosis, therapy, prognosis predition, personalized therapy