Abstract:

Objective To investigate the role of transcranial doppler ultrasonography (TCD) and plasma adrenomedullin (ADM) in evaluation of vertebrobasilar ischemia (VBI). Methods The data of TCD of 50 patients with VBI (VBI group) were analysed. The systolic velocity (Vs), diastolic velocity (Vd), mean velocity (Vm), pulsatility index (PI) and plasma ADM of vertebral artery (VA) and basilar artery (BA) of VBI group were recorded, and were compared with those of 50 healthy normal people (control group). Results The parameters of Vm, Vs and Vd of VA and BA in VBI group were significantly lower than those in control group (P<0.05), and PI in VBI group was significantly higher than that in control group (P<0.05). The plasma ADM in VBI group was significantly higher than that in control group (P<0.05). Conclusion TCD combined with plasma ADM can serve in the evaluation of disease condition and treatment in patients with VBI.

Key words: transcranial doppler ultrosonography, vertebrobasilar ischemia, plasma adrenomedullin