Journal of Shanghai Jiao Tong University (Medical Science) >

2021 , Vol. 41 >Issue 5: 628 - 631

DOI: https://doi.org/10.3969/j.issn.1674-8115.2021.05.011

Clinical research

Clinical features of 119 old patients with respiratory virus infection

  • Dao HUANG ,
  • Dong WEI ,
  • Zhi-hong XU ,
  • Jia-an HU
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  • 1.Department of Geriatrics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    2.Clinical Virology Laboratory, Institute of Infectious and Respiratory Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Online published: 2021-05-27

Supported by

Scientific Research Project of Shanghai Municipal Commission of Health and Family Planning(201840083);Important Weak Discipline Construction Program of Shanghai Municipal Commission of Health and Family Planning(2015ZB0503);Shanghai Universities Research Project of Production, Education and Research(RC20190079)

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Abstract

Objective

·To analyze the clinical features and risk factors that possibly affect the clinical outcome of elderly patients with respiratory virus infection.

Methods

·A total of 119 hospitalized patients (≥65 years old) with respiratory virus infection in the Department of Geriatrics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine were enrolled in this study. The clinical symptoms, laboratory examination, treatment course and outcome were analyzed and compared between cured patients and dead patients.

Results

·The average age of the patients was (85.61±7.67) years old, the male to female ratio was 98∶21 and 12 cases were dead. The number of influenza A virus patients (41 cases) was the most. Compared with cured patients, the dead patients were older, and the proportion of cases with bacterial infection or with double pneumonia in chest CT was higher (P<0.05). In the laboratory examination on admission, there were significant differences between the cured patients and the dead patients on leukocyte count, neutrophil count, erythrocyte count, the levels of hemoglobin, serum albumin, urea, and creatinine, and estimated glomerular filtration rate (P<0.05).

Conclusion

·Older age, higher leukocyte count and neutrophil count, lower hemoglobin and albumin levels, renal insufficiency and bacterial infection may be the influencing factors of death in elderly patients with respiratory virus infection.

Key words： the elderly; respiratory virus infection; clinical features

Cite this article

Dao HUANG , Dong WEI , Zhi-hong XU , Jia-an HU . Clinical features of 119 old patients with respiratory virus infection[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2021 , 41(5) : 628 -631 . DOI: 10.3969/j.issn.1674-8115.2021.05.011

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