Journal of Shanghai Jiao Tong University (Medical Science) >

2021 , Vol. 41 >Issue 11: 1425 - 1428

DOI: https://doi.org/10.3969/j.issn.1674-8115.2021.11.004

Disorders of sex development in children

Report of 3 cases of 47,XXX syndrome with growth retardation

  • YANG-Li ,
  • Ya-qin FENG ,
  • Yu YANG ,
  • Li-ling XIE ,
  • Di-lan WANG ,
  • Hui HUANG
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  • Department of Endocrinology, Genetics and Metabolism, Children's Hospital of Nanchang University/Jiangxi Provincial Children's Hospital, Nanchang 330006, China
YANG Yu, E-mail: yangyu5168@126.com.

Online published: 2021-10-22

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Abstract

To analyze the clinical data of 3 children with growth retardation, including height, chromosome karyotype, and the levels of growth hormone, insulin-like growth factor-1 and gonadal development. All the 3 cases of children were found to be slow in growth rate, no special face, and normal level of insulin-like growth factor-1; the 3 cases all underwent growth hormone provocation test, of which 1 case was partial growth hormone deficiency and 2 cases were idiopathic short; 3 cases of chromosomal karyotypes were 47, XXX, in line with the diagnosis of super-female syndrome.

Key words： 47, XXX syndrome; growth retardation; chromosomal disease; child

Cite this article

YANG-Li , Ya-qin FENG , Yu YANG , Li-ling XIE , Di-lan WANG , Hui HUANG . Report of 3 cases of 47,XXX syndrome with growth retardation[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2021 , 41(11) : 1425 -1428 . DOI: 10.3969/j.issn.1674-8115.2021.11.004

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