Journal of Shanghai Jiao Tong University (Medical Science) >

2022 , Vol. 42 >Issue 12: 1693 - 1698

DOI: https://doi.org/10.3969/j.issn.1674-8115.2022.12.006

Clinical research

Analysis of therapeutic effect of mindfulness-based intervention on inpatients with chronic schizophrenia

  • Hui SHEN ,
  • Yuejuan WU ,
  • Huijuan ZHU ,
  • Chuchen XU ,
  • Li ZHANG ,
  • Qing FAN
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  • 1.Department of Rehabilitation, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 201108, China
    2.Department of Rehabilitation, Mental Health Center of Xuhui District, Shanghai 200232, China
    3.Shanghai Institute of Traditional Chinese Medicine for Mental Health, Shanghai 201108, China
FAN Qing, E-mail: fanqing@smhc.org.cn.

Received date: 2022-07-27

  Accepted date: 2022-11-17

  Online published: 2022-12-28

Supported by

Three-year Action Plan of Shanghai to Further Accelerate the Inheritance, Innovation and Development of Traditional Chinese Medicine (2021?2023) [ZY (2021-2023)-0105];Clinical Medicine Project of Shanghai Science and Technology Committee Project(19411950800);Science Fund of Shanghai Jiao Tong University(YG2021QN135)

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Abstract

Objective ·To investigate the therapeutic effect of mindfulness-based intervention (MBI) on inpatients with chronic schizophrenia. Methods ·A total of 96 patients with chronic schizophrenia hospitalized in Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine from April to June 2021 were enrolled. They were divided into MBI group (n=48) and control group (n=48) by using random number table. The patients in the MBI group were combined with 5-week MBI on the basis of routine treatment, while the patients in the control group were maintained with routine treatment for 5 weeks. The general data of patients were collected, and the scores of Positive and Negative Syndrome Scale (PANSS), Freiburg Mindfulness Inventory (FMI) and Self-compassion Scale (SCS) were compared between the two groups at baseline and 5 weeks later. Results ·In general data, only the gender difference between the two groups was statistically significant (P=0.041). At baseline, there was no statistically significant difference between the two groups in the total scores of PANSS, FMI and SCS and their factor scores. After 5 weeks, the general psychopathology score of PANSS in the MBI group was lower than that in the control group (PBonferroni= 0.044), the total score and acceptance score of FMI were higher than those in the control group (PBonferroni=0.018, PBonferroni=0.003), and the total score of SCS was also higher than that in the control group (PBonferroni=0.000). Conclusion ·MBI can significantly improve mindfulness level and self-compassion ability of hospitalized patients with chronic schizophrenia, and promote the improvement of general psychopathology symptom, which is conducive to rehabilitation.

Key words： chronic schizophrenia; psychiatric symptom; mindfulness; self-compassion

Cite this article

Hui SHEN , Yuejuan WU , Huijuan ZHU , Chuchen XU , Li ZHANG , Qing FAN . Analysis of therapeutic effect of mindfulness-based intervention on inpatients with chronic schizophrenia[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022 , 42(12) : 1693 -1698 . DOI: 10.3969/j.issn.1674-8115.2022.12.006

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