Journal of Shanghai Jiao Tong University (Medical Science) >

2022 , Vol. 42 >Issue 12: 1729 - 1738

DOI: https://doi.org/10.3969/j.issn.1674-8115.2022.12.011

Public health

Development and validation of a knowledge, attitude, belief and practice scale for safe medication in patients with chronic kidney disease

  • Shan WEI ,
  • Ouyang JI ,
  • Zhihao CHEN ,
  • Zehui HUANG ,
  • Pu LI ,
  • Junyan FANG ,
  • Yingli LIU
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  • Department of Nephrology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China
LIU Yingli, E-mail: 18616375719@163.com.

Received date: 2022-04-19

  Accepted date: 2022-11-21

  Online published: 2022-12-28

Supported by

National Natural Science Foundation of China(8217030178);Special Subject of Clinical Research of Shanghai Municipal Health Commission(202140430);Clinical Research Program of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine(JYLJ2018011)

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Abstract

Objective ·To develop a knowledge, attitude, belief and practice (KABP) scale for safe medication in patients with chronic kidney disease (CKD), and test its reliability and validity. Methods ·Based on the KABP theory, the initial items were discussed and designed comprehensively by research group members through a systematic literature review and semi-structured interviews. The Delphi method of expert panel consultation and the pre-investigation were conducted to improve the initial scale. Next, the patients with CKD in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine were enrolled to complete the initial scale. The item analysis was conducted by critical ratio and homogeneity test. The construct validity and the content validity of scale were tested by exploratory factor analysis (EFA) and logic analysis, respectively. The reliability of the scale was evaluated by Cronbach's α coefficient, split-half reliability, and test-retest reliability. Results ·The initial scale consisted of 29 items with three dimensions. A total of 213 questionnaires were distributed and 209 valid questionnaires were collected. Items No.1, 2, 3 and 19, which did not meet the criteria of three or more indicators, were deleted after item analysis. The KMO (Kaiser-Meyer-Olkin) was 0.946, and the χ2 value of Bartlett's spherical test was 4 554.451 (P=0.000). The results suggested that the overall correlation matrix had common factors, which was suitable for factor analysis. The principal component analysis and the maximum variation method of orthogonal rotation axis were adopted. Item No.13 was deleted finally. According to the variable characteristics contained in each factor, three extracted common factors were named as "Practice of safe medication", "Knowledge about safe medication", and "Belief of safe medication", respectively. The eigenvalues of three dimensions were 6.565, 6.176, and 3.863, respectively, and the cumulative variance contribution rate was 69.18%. The scale-level-content validity index (S-CVI)/universal agreement was 0.860. The S-CVI/average was 0.987. The formal scale was formed of 24 items with three dimensions. The α coefficient of the total scale was 0.964. The split-half reliability coefficient was 0.911 and the test-retest reliability was 0.892 for the scale. Conclusion ·The KABP scale of safe medication in CKD patients has good reliability and validity.

Key words： chronic kidney disease (CKD); safe medication; knowledge, attitude, belief and practice (KABP) theory; scale

Cite this article

Shan WEI , Ouyang JI , Zhihao CHEN , Zehui HUANG , Pu LI , Junyan FANG , Yingli LIU . Development and validation of a knowledge, attitude, belief and practice scale for safe medication in patients with chronic kidney disease[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2022 , 42(12) : 1729 -1738 . DOI: 10.3969/j.issn.1674-8115.2022.12.011

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