Research progress on relationship between NMDA receptors and learning and memory
Online published: 2010-10-27
Supported by
National Natural Science Foundation of China, 30400421, 30901410
Long-term potentiation (LTP) is thought to be a model for neuronal plasticity and the neuro-biochemical base of learning and memory. The studies of LTP molecular mechanism focus mainly on N-methyl-D-aspartate (NDMA) receptors. Various combinations of subunits including NR1, NR2, NR3 assemble to form NMDAR and generate diversity in its functions. The effects of NMDA receptors on learning and memory are reviewed in this paper.
Key words: N-methyl-D-aspartate receptor; long-term potentiation; learning; memory
LI Qiang . Research progress on relationship between NMDA receptors and learning and memory[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2010 , 30(10) : 1285 . DOI: 10.3969/j.issn.1674-8115.2010.10.024
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