Review

Research progress of molecular mechanism in primary hyperaldosteronism

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  • Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China

Online published: 2013-05-28

Supported by

Shanghai Natural Science Foundation,10411960000

Abstract

Primary hyperaldosteronism (PA) is the most common form of endocrine hypertension. With the deepening of studies, the understanding of the pathogenesis of PA has been greatly improved. Elucidating the molecular mechanism of PA has far-reaching significance for a better understanding and therapeutic strategy of PA. In this paper, the abnormalities of ion channel activity, signaling pathways, and gene expression in PA are reviewed, and new ideas are expected to achieve for further research.

Cite this article

HUANG Bao-xing, SUN Fu-kang . Research progress of molecular mechanism in primary hyperaldosteronism[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2013 , 33(5) : 685 . DOI: 10.3969/j.issn.1674-8115.2013.05.036

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