›› 2013, Vol. 33 ›› Issue (5): 685-.doi: 10.3969/j.issn.1674-8115.2013.05.036

• Review • Previous Articles     Next Articles

Research progress of molecular mechanism in primary hyperaldosteronism

HUANG Bao-xing, SUN Fu-kang   

  1. Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2013-05-28 Published:2013-05-28
  • Supported by:

    Shanghai Natural Science Foundation,10411960000


Primary hyperaldosteronism (PA) is the most common form of endocrine hypertension. With the deepening of studies, the understanding of the pathogenesis of PA has been greatly improved. Elucidating the molecular mechanism of PA has far-reaching significance for a better understanding and therapeutic strategy of PA. In this paper, the abnormalities of ion channel activity, signaling pathways, and gene expression in PA are reviewed, and new ideas are expected to achieve for further research.

Key words: primary hyperaldosteronism, ion channel, signaling pathway, gene expression