上海交通大学学报（医学版）

上海交通大学学报（医学版）

• 论著（临床研究） • 上一篇    下一篇

2型糖尿病患者胃排空影响因素的研究

冯日露 1，金云秋 1，徐华 1，宋少莉 2，刘伟 1，麻静 1   

  1. 上海交通大学医学院附属仁济医院 1.内分泌科，2.核医学科，上海 200127
  • 出版日期:2017-05-28 发布日期:2017-05-31
  • 通讯作者: 麻静，电子信箱：cherry1996@live.cn。
  • 作者简介:冯日露（1991—），女，硕士；电子信箱：rilu_feng@163.com。
  • 基金资助:

    国家自然科学基金（81670728）；上海市科委基金（14441903502）；上海交通大学医学院附属仁济医院临床科研创新培育基金计划（PYZY16-020）

Study on factors affecting the gastric emptying in patients with type 2 diabetes mellitus
#br#  

FENG Ri-lu1, JIN Yun-qiu1, XU Hua1, SONG Shao-li2, LIU Wei1, MA Jing1   

  1. 1.Department of Endocrinology, 2. Department of Nuclear Medicine,Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Online:2017-05-28 Published:2017-05-31
  • Supported by:

    Natural Science Foundation of China, 81670728；Science and Technology Commission of Shanghai Municipality, 14441903502；Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, PYZY16-020

PDF (PC)

836

摘要：

目的 ·探讨 2型糖尿病患者胃排空速率的可能影响因素。方法 ·选取 2013年9月—2014年3月上海交通大学医学院附属仁济医院内分泌科收治的94例2型糖尿病患者作为研究对象，对胃排空速率指标半排空时间（T1/2）及食物在胃内2 h滞留率（R120 min）进行检测。结果 ·与男性患者比较，女性患者T1/2较长（P=0.000），R120 min较高（P=0.000）；胃排空正常组与延迟组之间的年龄、病程、体质量指数、血糖水平、糖尿病慢性并发症及胃肠道症状的差异无统计学意义，且阿卡波糖对2型糖尿病患者的胃排空速率无影响。结论 · 2型糖尿病患者的胃排空速率与性别有关，与血糖水平、糖尿病慢性并发症、胃肠道症状及是否使用阿卡波糖无明显相关。

关键词:  , 胃排空速率；2 型糖尿病；性别；血糖；并发症

Abstract:

Objective · To investigate the possible factors affecting the gastric emptying rate in patients with type 2 diabetes mellitus. Methods · 94 type 2 diabetic patients treated at the Department of Endocrinology of Renji Hospital affiliated to Shanghai Jiao Tong University School of Medicine from September 2013 to March 2014 were enrolled. The half gastric emptying time (T1/2) and retention at 120 min (R120 min) were measured. Results · Female patients had longer T1/2 (P=0.000) and higher R120 min (P=0.000) than male patients. The differences in age, duration of diabetes, BMI, blood glucose level, chronic diabetic complications, and gastrointestinal symptoms between normal and delayed gastric emptying groups were not statistically significant. Acarbose had no effect on the gastric emptying rate in type 2 diabetic patients. Conclusion · The gastric emptying rate in type 2 diabetic patients is associated with the gender and has no significant correlation with blood glucose level, chronic diabetic complications, gastrointestinal symptoms, and acarbose.

Key words: gastric emptying rate, type 2 diabetes, gender, blood glucose, complication