上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2017, Vol. 37 ›› Issue (6): 758-.doi: 10.3969/j.issn.1674-8115.2017.06.008

• 论著（临床研究） • 上一篇    下一篇

基于三维打印技术的人工骨修复下颌骨缺损 149 例临床分析

ZIN Mar Aung*，韩文卿 *，陈骁俊，林力，张艳，徐海淞，柴岗   

  1. 上海交通大学 医学院附属第九人民医院整复外科，上海 200011
  • 出版日期:2017-06-28 发布日期:2017-07-05
  • 通讯作者: 柴岗，电子信箱：13918218178@163.com
  • 作者简介:?ZIN Mar Aung（1990—），女，硕士生；电子信箱：2660252361@qq.com。韩文卿（1994—），女，本科生；电子信箱：303061387@qq.com。*共同第一作者。
  • 基金资助:

     国家自然科学基金（81372097）；上海市科学技术委员会项目（14441900800，14441900802）；上海交通大学医工交叉研究基金（YG2014MS06）； 上海市教育委员会高峰高原学科建设计划（20161420）

Clinical analysis of mandibular reconstructions using synthetic bones based on three-dimensional printing technology in 149 cases

ZIN Mar Aung*, HAN Wen-qing*, CHEN Xiao-jun, LIN Li, ZHANG Yan, XU Hai-song, CHAI Gang   

  1. Department of Plastic and Reconstructive Surgery, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
  • Online:2017-06-28 Published:2017-07-05
  • Supported by:

    National Natural Science Foundation of China, 81372097; Project of Science and Technology Commission of Shanghai Municipality, 14441900800, 14441900802; Research Fund of Shanghai Jiao Tong University, YG2014MS06; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support, 20161420

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摘要：

目的 · 通过回顾性研究计算机辅助三维重建技术设计、制造人工骨精确修复下颌骨缺损的经验，评估其临床应用价值。
 方法 · 选择 2001—2016 年在上海交通大学医学院附属第九人民医院整复外科颅颌面中心治疗下颌骨缺损的患者，对随访半年以上的 患者进行三维重建 CT 影像测量数据；随机测量术前、术后 3 个关键解剖点并进行误差统计，评估计算机辅助三维重建技术在修复下 颌骨缺损中的精度价值；回顾性统计手术时间、术中并发症等指标，进一步探究其临床应用价值。结果 · 2001 年 7 月至 2016 年 7 月 共有 163 例患者接受了计算机辅助三维重建人工骨修复治疗下颌骨缺损，其中 149 患者满足统计条件；术前设计与术后实际效果的平 均距离误差为（1.27±0.15）mm，手术时间为（2.5±1.2）h，未发生术中并发症。结论 · 三维设计打印人工骨是一种精确修复下颌骨 缺损的可靠技术，依靠定量设计及术前模拟，简化了手术难度，提高了手术精度，患者满意度较高，手术并发症少且长远疗效可靠。

关键词: 计算机辅助外科, 下颌骨重建, 人工骨, 三维打印

Abstract:

Objective · To assess the clinical value of the computer-assisted three-dimensional reconstruction technique design and evaluate the clinical experience of manufacture artificial bone precision to repair the mandibular defect.  Methods · From 2001 to 2016, 163 computer-assisted reconstruction surgeries had been performed in Craniofacial Department, Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine. During six months followup, the measurement data was conducted and compared with three-dimensional CT result. Random measurement of the three key anatomical points pre- and post-operative carried out with statistical error was used to evaluate the accuracy of computer-assisted three-dimensional reconstruction in mandibular defects repairation and to investigate the clinical application value of the operation time and postoperative complication rate.  Results · From July 2001 to July 2016, a total of 163 patients underwent computer-assisted three-dimensional reconstruction of artificial bone repair for mandibular defects; 149 patients met the statistical criteria in which preoperative design and postoperative actual effect’s average distance error (1.27±0.15) mm, operation time (2.5±1.2) h.  Conclusion · Threedimensional design of artificial bone to repair the mandibular defect is a valuable technology, by relying on quantitative design and preoperative simulation to simplify the difficulty and improve the accuracy of surgery. The patients showed high satisfaction rate with low surgical complications and long-term efficacy.

Key words:  computer-assisted surgery, mandibular reconstruction, synthetic bone, three dimensional printing