糖尿病视网膜病变患者血清转化生长因子β水平研究
网络出版日期: 2013-08-22
基金资助
上海市眼底病重点实验室开放课题基金(07Z22911)
Serum transforming growth factor-β levels in patients with diabetic retinopathy
Online published: 2013-08-22
Supported by
Shanghai Key Laboratory for Ocular Fundus Disease Foundation, 07Z22911
罗大卫 , 郑 志 , 刘 堃 , 等 . 糖尿病视网膜病变患者血清转化生长因子β水平研究[J]. 上海交通大学学报(医学版), 2013 , 33(7) : 990 . DOI: 10.3969/j.issn.1674-8115.2013.07.019
Objective To investigate the serum transforming growth factor-β (TGF-β) levels in patients with diabetic retinopathy (DR). Methods Seventy-two patients with diabetes were selected, including 15 patients with proliferative diabetic retinopathy (PDR group), 32 patients with non-proliferative diabetic retinopathy (NPDR group) and 25 patients with non-diabetic retinopathy group (NDR group). Besides, 45 healthy people were served as normal control group. The serum TGF-β levels were detected by ELISA. Results Serum TGF-β levels in groups with diabetes were significantly higher than that in normal control group (P<0.01). Serum TGF-β level in PDR group was significantly higher than those in NPDR group and NDR group (P<0.05). Conclusion Serum TGF-β level is associated with the severity of diabetic retinopathy.
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