目的 观察不同脱敏剂治疗牙颈部牙本质敏感症的临床疗效。方法 76例牙颈部牙本质敏感症患者共214颗患牙根据敏感程度分为中等症状组（n=110）和重症组（n=104），分别采用Clinpro TM XT Varnish、Gluma脱敏剂和75%氟化钠甘油糊剂进行脱敏治疗，观察治疗后即刻的脱敏效果，并于治疗后1、3、6个月时复查，计算治疗有效率。结果 治疗后即刻及1、3、6个月复查时，三种脱敏剂的治疗有效率在中等症状组与重症组间比较，差异均无统计学意义（P>0.05）。组内比较结果显示：Clinpro TM XT Varnish和Gluma脱敏剂的治疗后即刻疗效优于氟化钠甘油（P<0.05）。随着时间的延长，三组疗效均有下降，治疗后6个月时，Clinpro TM XT Varnish的治疗有效率高于Gluma脱敏剂和75%氟化钠甘油糊剂（P<0.05）。结论 三种脱敏剂均可缓解牙颈部牙本质敏感症状，Clinpro TM XT Varnish有较好的远期疗效。

Objective To observe the clinical effects of different desensitizers on cervical dentin hypersensitivity. Methods Seventy-six patients (214 teeth) with cervical dentin hypersensitivity were divided into moderate symptom group (n=110) and severe symptom group (n=104) according to the severity of hypersensitivity. Desensitization was randomly performed with Clinpro TMXT Varnish, Gluma and 75% sodium fluoride glycerol in each group. The efficacy was evaluated immediately after treatment and 1 month, 3 months and 6 months after treatment, and the effective rates were calculated. Results There was no significant difference in the effective rates immediately after treatment and 1 month, 3 months and 6 months after treatment between moderate symptom group and severe symptom group (P>0.05). The efficacy of Clinpro TMXT Varnish and Gluma was better than that of sodium fluoride glycerol immediately after treatment within the same group (P<0.05). The efficacy decreased with time for all the three desensitizers. Six months after treatment, the effective rate of Clinpro TMXT Varnish was higher than those of Gluma and 75% sodium fluoride glycerol (P<0.05). Conclusion All the three desensitizers may play a role in the treatment of cervical dentin hypersensitivity, and Clinpro TMXT Varnish may yield better long-term effects.