抗苗勒管激素与妇科肿瘤相关性的研究进展
Advances of relationship between anti-Müllerian hormone and gynecologic oncology
Online published: 2014-01-29
纪晓宁 , 丰有吉 . 抗苗勒管激素与妇科肿瘤相关性的研究进展[J]. 上海交通大学学报(医学版), 2014 , 34(1) : 109 . DOI: 10.3969/j.issn.1674-8115.2014.01.023
The understanding and application of anti-Müllerian hormone (AMH) were mainly limited to gynecology reproductive endocrinology in the past days. While in recent years, more studies have been focusing on the correlation between AMH and gynecologic oncology. In accordance with the present research, granulosa cell tumor (GCT) of ovary has the highest correlation with AMH,which has been proven to be an effective serum tumor marker in clinical practice for early diagnosis, therapeutic effect evaluation, prognostic evaluation, and recurrence monitoring. The further researches find that AMH can also significantly inhibit epithelial ovarian cancer cells, so it promises to be a new auxiliary therapy for epithelial ovarian cancer. Additionally, the correlation between AMH and cervical cancer and whether it may be a new targeted therapy are worthy of further studying.
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