目的 研究不同介质（空气、水和釉液）在不同基底色时对全瓷贴面颜色的影响。方法 将不同基底色组（ND1~ND7）试件与IPS e.max CAD LTA1 0.7 mm瓷片叠合，采用测色仪对修复体贴面进行测量，并以2 mm LTA1、LTA2色瓷块颜色为标准色计算色差（ΔE值）；以ND1~ND6的ΔE值为因变量分别进行两因素方差分析，多重对比采用Tamhane T2检验。结果 介质和基底色对贴面与标准色之间的ΔE值均有影响，并且两因素之间存在交互作用(P<0.05)。空气与水、空气与釉液之间ΔE值的差异均有统计学意义（P<0.05），而水与釉液之间ΔE值的差异无统计学意义（P>0.05）；不同介质对修复体明度改变的影响最为显著。结论 介质空气、水和釉液对全瓷贴面颜色均有影响，其中对明度的影响最为明显。基底色与介质之间存在交互作用，水与釉液能使贴面更接近于目标色。贴面与基底牙之间保持一定的湿润度更有利于比色。

Objective To investigate the effects of different mediums (air, water, and glaze liquid) and different abutment colors on the final color of all-ceramic veneer. Methods Specimens of different abutment colors (ND1-ND7) and IPS e.max CAD LTA1 0.7 mm ceramics slices were superposed and the final color of veneers of restorations was measured by the color spectrometer. The color difference (ΔE) was calculated according to reference colors of 2 mm LTA1 and LTA2 ceramic blocks. Two-way ANOVA analysis was carried out based on ΔE values of ND1-ND6 and Tamhane T2 test was performed for multiple comparisons. Results Both mediums and abutment colors affected ΔE values and the interactive effect existed between two factors (P<0.05). The differences of ΔE values of air and water, and air and glaze liquid were statistically significant (P<0.05), while the differences of ΔE values of water and glaze liquid were not statistically significant (P>0.05). The effect of different mediums on the lightness of restorations was the most significant. Conclusion All of mediums air, water, and glaze liquid affect the color of allceramic veneer. The effect of mediums on the lightness is the most significant. The interactive effect exists between mediums and abutment colors. Water and glaze liquid can make the color of all-ceramic veneer closer to the target color. Maintenance of a certain degree of moisture benefits the color matching.