精子鞭毛结构蛋白研究进展
网络出版日期: 2015-09-30
基金资助
上海交通大学医学院附属仁济医院种子基金(RJZZ14-017);国家自然科学基金(30973069,30672146)
Research advances of structural proteins of sperm flagella
Online published: 2015-09-30
Supported by
Foundation of Renji Hospital, Shanghai Jiao Tong University School of Medicine, RJZZ14-017; National Natural Science Foundations of China, 30973069, 30672146
宋平平 , 邹沙沙 , 李铮 , 等 . 精子鞭毛结构蛋白研究进展[J]. 上海交通大学学报(医学版), 2015 , 35(9) : 1384 . DOI: 10.3969/j.issn.1674-8115.2015.09.028
The flagellum is the motility organ of mature sperms and its microtubule based axoneme structure is highly conservative during evolution. The defect or missing of sperm flagella protein, which is relevant to the structure and function of sperms, can lead to motility dysfunction of sperms and cause male infertility. This paper reviews the latest research advances of molecules relevant to the formation and motility of sperm tails. Problems of structure and function of these molecules are closely related to many clinical diseases.
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