慢性阻塞性肺疾病发生相关因素的研究进展
网络出版日期: 2016-02-26
基金资助
国家自然科学基金(91129303)
Advances of relevant factors to incidence of chronic obstructive pulmonary disease
Online published: 2016-02-26
Supported by
National Natural Science Foundation of China, 91129303。
赵振钧 , 邓炯 . 慢性阻塞性肺疾病发生相关因素的研究进展[J]. 上海交通大学学报(医学版), 2016 , 36(1) : 128 . DOI: 10.3969/j.issn.1674-8115.2016.01.026
The chronic obstructive pulmonary disease (COPD) is a chronic pulmonary disease featured by airflow obstruction. The fatality rate of COPD has risen to the fourth among all diseases in the world. The main characteristics are persistent obstruction, chronic inflammation, and remodeling of small airways, which slow down the airflow and weaken the elastic retraction of alveoli. In China, the incidence and fatality rate of COPD rise year by year due to cigarette smoking and air pollution. This paper reviews factors and possible mechanisms of the incidence and development of COPD from perspectives of environmental factors and cellular, sub-cellular, and molecular levels.
/
〈 |
|
〉 |