目的 探讨精神康复干预（PRI）和事件相关脑电位（ERP）诊疗新技术联合应用在精神分裂症康复中的作用及干预效果。方法 将96例精神分裂症患者随机分成研究组和对照组，每组48例。采用PRI和ERP对精神分裂症进行康复治疗。结果 ①实施PRI后，研究组患者的简明精神病评定量表（BPRS）、社会功能缺陷测定（SDSS）减分值以及治疗依从性问卷增分值均显著高于对照组(P<0.05或0.01)。②实施PRI后，研究组患者家属的精神症状自评量表（SCL-90）各因子减分值显著高于对照组(P<0.05或0.01)。③研究组随着症状缓解，ERP检测中的主要指标靶刺激P2、P3波幅也随之改善（P<0.05或0.01）。结论 PRI治疗对患者恢复社会功能、患者家属心理健康状况均有显著的效果。

Objective To explore the effects of novel diagnosis and treatment technologies combination of psychic rehabilitation intervention (PRI) and event related potentials (ERP)  applied to the rehabilitation of schizophrenia and intervention outcomes. Methods Ninety-six patients with schizophrenia were randomly assigned to the study group and the control group with 48 patients per group. PRI and ERP were used to perform rehabilitation treatment for patients. Results ①After the implementation of PRI, the decrease in the scores of Brief Psychiatric Rating Scale (BPRS) and Social Disability Screening Schedule (SDSS) and the increase in the scores of Medication Adherence Rating Scale (MARS) in the study group were greater as compared with the control group (P<0.05 or 0.01). ②After the implementation of PRI, the decrease in the scores of all factors in Symptom Checklist 90 (SCL-90) in the study group were much greater as compared with the control group (P<0.05 or 0.01). ③For the study group, P2, P3 amplitudes of the target stimulus, which were major indexes in ERP test, improved with the remission of symptoms (P<0.05 or 0.01). Conclusion PRI treatment has significant efficacy for improving patients social functions and family members mental health.