医学研究有基础生物医学研究和临床医学研究两种范式。临床医学研究目前存在思想认识不足、研究投入不够、高端人才匮乏、评价体系不完善、数据有待整合等问题。加强临床医学研究，需要着力把握以下关键环节：以研究型医师和临床专职科研人员两支队伍为依托，通过转变思路理念，变临床资源为科研资源；改革体制机制，引育人才并激发人才活力；加大资金投入，增强科研项目经费的导向作用；构筑数据平台，整合建立规范的生物样本库和统一的数据库；加强国际合作，加快构建全球范围的多中心临床研究协作网络等。

Medical research includes basic biomedical research and clinical research. The latter is limited by multiple factors including the failure to appreciate the significance of clinical research, the lack of research funding and specialized teams, the improper evaluation system, the lack of the standardization in data integration and so on. Therefore, the following steps should be taken to strengthen the clinical research. Firstly, the teams of research doctors and clinical scientific researcher have to be constructed, and clinical resources have to be converted into research resources by embracing novel concepts. Secondly, the institutional infrastructure should be transformed to recruit, educate and motivate the excellent researchers and clinicians. Thirdly, the investment should be increased, and the guidance of scientific research funding should be strengthened. Fourthly, the data platform , standardized biobank and unified database system have to be built. Finally, the international collaboration should be strengthened, and the building of multicenter research network for randomized controlled trials should be speed up.