综述

眼球运动在帕金森病中的研究进展

  • 周立彻 ,
  • 刘军
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  • 1.上海交通大学 医学院, 上海 200025; 2.上海交通大学 医学院附属瑞金医院神经内科, 上海 200025
周立彻(1992—), 男, 八年制博士研究生; 电子信箱: zlclich-47@sjtu.edu.cn。

网络出版日期: 2016-10-31

基金资助

上海市教育委员会高峰高原学科建设计划(20152201)

Research progresses of eye movement in Parkinsons disease

  • ZHOU Li-che ,
  • LIU Jun
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  • 1.Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2.Department of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Online published: 2016-10-31

Supported by

Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support,20152201

摘要

帕金森病是一种症状多样、机制复杂的神经退行性疾病。近年来,随着对帕金森病致病机制、生物标志物等研究的深入,越来越多的研究者发现眼球运动的异常在帕金森病中有着重要的意义。该文主要总结了近10余年来国内外学者对于眼球运动异常和帕金森病的相关研究,并对其病理生理机制、临床研究的设计和作为生物标志物对帕金森病的诊断与鉴别的价值进行了初步的探讨。

本文引用格式

周立彻 , 刘军 . 眼球运动在帕金森病中的研究进展[J]. 上海交通大学学报(医学版), 2016 , 36(9) : 1399 . DOI: 10.3969/j.issn.1674-8115.2016.09.027

Abstract

Parkinsons disease is a multifaceted neurodegenerative disorder with complicated mechanism and various symptoms. In recent years, with the deepening of the research on the pathogenesis and biomarkers of Parkinsons disease, a growing number of researchers have found that eye movement abnormalities play an important role in Parkinsons disease. This paper mainly summarizes the latest research progresses of eye movement disorders and Parkinsons disease, and explores pathophysiological mechanism, design of clinical research, and the value of eye movement as a biomarker in diagnosis and differentiation of Parkinson’s disease.

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