加速度测量和表面肌电图检测对帕金森病震颤与特发性震颤的鉴别诊断价值
网络出版日期: 2017-01-19
基金资助
国家自然科学基金 (81171202, 81471287)
Value of acceleration and surface electromyogram signals in discriminating tremor between Parkinson’s disease and essential tremor
1.Department of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2. State Key Laboratory of Mechanical System and Vibration, Shanghai Jiao Tong University, Shanghai 200240, China; 3. Department of Neurology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201999, China
Online published: 2017-01-19
Supported by
National Natural Science Foundation of China,81171202,81471287
黄菲菲 , 张斌 , 吴丹红 , 张定国 , 刘军 . 加速度测量和表面肌电图检测对帕金森病震颤与特发性震颤的鉴别诊断价值[J]. 上海交通大学学报(医学版), 2017 , 37(1) : 34 . DOI: 10.3969/j.issn.1674-8115.2017.01.008
Objective · To investigate the clinical value of acceleration and surface electromyogram (sEMG) signals in discriminating tremor between Parkinson’s disease (PD) and essential tremor (ET). Methods · Twenty-four patients with Parkinson’s disease and 20 patients with ET were enrolled and tested with a new posture for tremor measurement (i.e, Posture 1), which the results were compared with those of anothertraditional posture (i.e, Posture 2). The comparing characteristics included amplitude, frequency and burst pattern of tremor. Results · As regarding amplitude of tremor, for Posture 1, the confidence intervel of mean value of tremor amplitude of PD and ET in the log scale was 0.75-2.40 and 0.81-3.11 with significant diffierence (F=51.1, P=0.000), respectively. While for Posture 2, there was 0.92-3.38 and 1.43-2.96 between PD and ET, respectively, without significant difference (F=0.14, P=0.709). For tremor frequency, there were significant difference between both postures (F1=97.2, P1=0.000; F2=15.2, P2=0.000). However, the coefficient
for discrimination increased by 148.1% from 0.27 to 0.67 when Posture 2 comparing to Posture 1. As for burst pattern of sEMG signals, there was no significant difference between PD and ET in sychronous or asychronous muscle activation pattern in both postures. Conclusion · The new posture for
tremor measurement could improve tremor discrimination between PD and ET.
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